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KMID : 0364020130460020111
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Korean Journal of Thoracic and Cardiovascular Surgery
2013 Volume.46 No. 2 p.111 ~ p.116
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Heart Transplantation in the Elderly Patients: Midterm Results
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Yeom Sang-Yoon
Hwang Ho-Young
Oh Se-Jin
Cho Hyun-Jai
Lee Hae-Young
Kim Ki-Bong
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Abstract
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Background: Heart transplantation in elderly patients has raised concerns because of co-morbidities and limited life expectancy in the era of donor shortage. We examined the outcomes after heart transplantation in elderly patients. Materials and Methods: From March 1994 to December 2011, 81 patients (male:female=64:17, 49.1±14.0 years) underwent heart transplantation. The outcomes after heart transplantation in the younger patients (＜60 years; group Y, n=60) were compared with those in the elderly patients (≥60 years; group O, n=21). The follow-up duration was 51.8±62.7 months. Results: Early mortality (≤30 days) occurred in 5.0% (3/60) and 4.8% (1/21) of groups Y and O, respectively (p＞0.999). There were no differences in overall survival between the two groups (p=0.201). Freedom from rejection was higher in group O than in group Y (p=0.026). Multivariable analysis revealed that age ≥60 years was not a significant risk factor for long-term survival; postoperative renal failure was the only significant risk factor for long-term survival (p=0.011). Conclusion: Early and mid-term results of heart transplantation in elderly patients were similar to those in younger patients.
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KEYWORD
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Heart transplantation, Outcome assessment, Elderly
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